Choose 'em: Edwin van der Sar (16.65) has gone a ridiculous 1,112 minutes without conceding a Premier League goal so why not back a winner this week. If you're not convinced, consider the fact Manchester United are playing twice in this round of Fantasy action - away to West Ham and home against Fulham.Another team up twice before we meet again are Manchester City, who will give a debut to new signing Shay Given (3.07) on Saturday. The Irish international keeper is a superb option unless you fancy either Middlesbrough or Portsmouth to go on a goal spree against Mark Hughes's team... we'll leave you to make a decision on the chances of that happening.
Lose 'em: West Brom have conceded eight times in their last three meetings with Newcastle, so it might be a good idea to avoid Scott Carson (6.73).Hull's Matt Duke (7.06) is also one to swerve, when you consider he will start between the sticks for the league's worst defence (46 conceded) against its best attack (Chelsea, 44 goals).Blackburn are unbeaten under Sam Allardyce and have only shipped five goals in nine games since the big man took over. For that reason how about a wager on Ryan Nelsen (6.29)?Lose 'em: Portsmouth's back four were appalling against Fulham last week, so it might be wise to avoid Sylvain Distin (8.40) and Younes Kaboul (7.94) for the visits of title contenders Liverpool and free-scoring Manchester City to Fratton Park.