Bayern and Wolfsburg are joint second on 48 points, a point behind leaders Hertha Berlin with nine matches left and a defeat for either would see them drift off at least three points.
Wolfsburg, with seven consecutive wins, have the league's most feared home record, dropping only two out of a possible 36 points from 12 matches.
Toni's return from a four-week absence with a heel injury is welcome news for Bayern who had been short of fit strikers after Miroslav Klose injured his ankle and was ruled out for more than a month, leaving volatile Lukas Podolski as the only option.
"Luca is hungry. He wants to get stuck in there," said Bayern coach Juergen Klinsmann after the Italian scored a hat-trick in training.